Antifreeze Proteins Market Size to Worth USD 167.63 Billion by 2034 | Towards FnB
According to Towards FnB, the global antifreeze proteins market size is calculated at USD 17.43 billion in 2025 and is accelerate sharply to USD 167.63 billion by 2034. This remarkable expansion represents a robust CAGR of 28.6%, underscoring the rapidly rising commercial relevance of AFPs across multiple high-growth industries.
Ottawa, Nov. 14, 2025 (GLOBE NEWSWIRE) -- The global antifreeze proteins market size stood at USD 13.55 billion in 2024 and is predicted to increase from USD 17.43 billion in 2025 to reach nearly USD 167.63 billion by 2034, according to a report published by Towards FnB, a sister firm of Precedence Research. This long-term forecast highlights the industry’s shift from niche scientific interest to mainstream commercial integration, supported by rising investment, expanding research pipelines, and increasing approval of AFP-based applications in regulated markets.
The accelerating growth of the antifreeze proteins market is driven by their expanding use in food preservation, cosmetic formulation stability, medical and pharmaceutical innovation, and advanced cryopreservation systems. AFPs offer unique functional benefits such as preventing ice crystal formation, reducing texture degradation, and enhancing cellular viability which are increasingly valued by manufacturers aiming to improve product quality, extend shelf life, and minimize reliance on synthetic additives. These performance advantages continue to fuel widespread interest across both established and emerging application areas.
Note: This report is readily available for immediate delivery. We can review it with you in a meeting to ensure data reliability and quality for decision-making.
Access the Full Study Instantly | Download Sample Pages of the Report Now@ https://www.towardsfnb.com/download-sample/5913
Key Highlights of Antifreeze Proteins Market
- By region, North America led the global antifreeze proteins market with a revenue share of 44% in 2024, while the Asia Pacific region is expected to grow at a 15.5% CAGR during the forecast period.
- By type, the Antifreeze Glycoproteins (AFGPs) segment accounted for a significant 45.9% of the market share in 2024. The Type III antifreeze protein segment is projected to grow at a 13.5% CAGR between 2025 and 2034.
- By source, the fish-derived antifreeze proteins segment captured 46.8% of the market revenue in 2024, whereas the recombinant/synthetic AFPs segment is expected to expand at a 13.6% CAGR between 2025 and 2034.
- By end use, the food processors and seafood industry dominated with a market share of 46.5% in 2024. The pharmaceuticals and biotech companies segment is projected to grow at 14.2% CAGR during the forecast period from 2025 to 2034.
Higher Demand for Improved Cold Chain Storage Is Helpful for the Growth of the Antifreeze Proteins Industry
The antifreeze protein market is expected to grow due to factors such as increased demand for food preservation, their use in medicinal and pharmaceutical applications, and their role in cryopreservation. The technologically advanced procedure involves slowing ice crystal formation and growth, lowering the freeze point, and reducing freeze-thaw damage in cells, tissues, and products. The procedure helps obtain biologically derived proteins and glycoproteins useful for various applications.
The market is also growing due to high demand for antifreeze proteins across food preservation, cryopreservation, pharmaceuticals, agriculture, cosmetics, and research. The array of benefits of antifreeze proteins includes improved quality of frozen products, enhanced quality of cold chain storage for biologics, and reduced cellular damage during extraction, recombinant production, and formulation services.
Impact of AI on the Antifreeze Proteins Market
Artificial intelligence is playing an increasingly important role in accelerating innovation within the antifreeze proteins market. AI tools allow researchers to analyse large molecular datasets and predict protein structures and binding behaviours with far greater accuracy than traditional modeling methods. This improves the discovery of new antifreeze protein variants and enables the optimisation of existing proteins for higher thermal stability, enhanced ice recrystallisation inhibition, and improved performance in food, cosmetic, and biomedical applications.
Machine-learning algorithms are also helping manufacturers identify the most efficient production pathways by screening microbial strains, fermentation conditions and purification steps. This reduces trial-and-error time in laboratory environments and supports the development of scalable, cost-effective production systems. AI-driven formulation tools help companies blend antifreeze proteins with other functional ingredients while maintaining stability across a range of temperatures, which is valuable for frozen food, cryopreservation products, and temperature-sensitive cosmetics.
Recent Development of Antifreeze Proteins Market
In October 2025, Researchers from the University of Utah’s John and Marcia Prince College of Engineering devised a synthetic version of a protein that can be manufactured at scale and is powerful enough to inhibit the formation of ice crystals. The study was funded by the National Science Foundation. (Source- https://attheu.utah.edu)
New Trends of Antifreeze Proteins Market
- Expanding applications of antifreeze proteins in the food, medical, cosmetics, and agricultural segments are one of the major factors for the growth of the market.
- Use of antifreeze proteins for technological and developmental research for new product innovation is another major factor for the growth of the market.
- Use of antifreeze proteins as an alternative to conventional chemicals to maintain sustainability is another major factor driving market growth.
- Higher demand for natural food additives to avoid chemical preservatives is also a vital factor for the growth of the market.
- Use of antifreeze proteins to enhance the shelf life, quality, and texture of various products of different domains is a vital factor for the growth of the market.
Technological Advancements are Helpful for the Antifreeze Proteins Market
The use of genetic engineering to produce low-immunogenic, functional versions; computational design to create specific, enhanced antifreeze proteins; and recombinant DNA technology to improve production help fuel the market's growth. Such technological improvements make antifreeze proteins more accessible and effective across a wide range of applications, including crop protection, food preservation, and medical cryopreservation. Recombinant DNA technology, which produces high-quality antifreeze proteins, making them more accessible for various applications, is another major advantage of the technology, helping drive market growth.
View Full Market Intelligence@ https://www.towardsfnb.com/insights/antifreeze-proteins-market
Antifreeze Proteins Market Dynamics
What are the Growth Drivers of the Antifreeze Proteins Market?
An array of advantages of antifreeze proteins is the biggest driver of market growth. Different types of benefits across domains help fuel market growth. Antifreeze proteins elevate the food and beverages industry by enhancing the quality, taste, and texture of frozen food options, and they also boost demand for the frozen sector, further fueling market growth. Antifreeze proteins are an ideal alternative to harmful chemicals and preservatives, making them a sustainable option that also supports market growth.
The use of antifreeze proteins for cryopreservation of biological materials, such as organs, tissues, and blood, for transplants and other medical procedures, is beneficial to the medical industry, further fueling market growth. They are also useful for drug delivery systems and tissue engineering. The use of antifreeze proteins to maintain the quality of skincare products further fuels the growth of the antifreeze proteins market.
Challenge
Production and Technical Issues Hamper the Market’s Growth
High production, innovation, and application costs can restrict the growth of the antifreeze proteins market. The extraction and purification of antifreeze proteins from natural sources, required for research purposes, is expensive. The scaling up of biological manufacturing from laboratory settings to industrial levels is another restriction on the market’s growth. Hence, such issues affect the market's growth in the foreseeable period.
Opportunity
Sustainability and Product Diversification Are Helpful for the Market’s Growth
Antifreeze proteins are derived from natural sources through different extensive and technological procedures. Hence, they are an ideal replacement for chemicals and preservatives, making them highly sought after across various sectors to promote sustainability. Hence, such pointers help fuel the market's growth. The availability of premium and organic products made with antifreeze proteins and free of chemical and harmful preservatives is another major factor fueling the market's growth.
For Detailed Pricing and Tailored Market Report Options, Click Here: https://www.towardsfnb.com/checkout/5913
Trade Analysis of the Antifreeze Proteins Market
Import & Export Perspectives
Demand Drivers That Shape Trade
- Global demand for antifreeze proteins is driven by applications with international supply chains: frozen food quality improvement, cryopreservation for biopharma and tissue banking, cosmetics, and specialty industrial uses. Recent reviews and journal articles document growing research and adoption in food and biomedical sectors, which creates trade flows for production inputs and finished AFP products. These applications are concentrated in markets with advanced food processing and biopharma industries, which are likely to shape import demand patterns.
Likely Exporter and Importer Profiles
- Because antifreeze protein production is biotechnically intensive, countries with strong biotech and fermentation capacity are the most likely exporters. In practice, this means production and export leadership is likely to come from biotech hubs in the European Union, the United States, and China, as well as from specialised contract manufacturing organisations in Asia. Import demand is likely to concentrate in countries with large frozen-food industries, expanding cell therapy and biobanking sectors, and active cosmetics manufacturing.
Recent Public Indicators and Market Size
- Peer-reviewed literature and reviews show accelerated R&D and pilot commercialisation of AFP applications in food and medical sectors, indicating that demand is growing even if trade remains small and specialist. The academic, evidence-based documents that AFP uses in frozen food quality and cryopreservation research, which underpin future trade potential as commercial scale-up proceeds.
Trade Policy, Regulatory, and Logistics Considerations
- Antifreeze protein shipments will be sensitive to biological product regulation, cold-chain requirements, and customs classification. Exporters must ensure product dossiers, safety data, and any required sanitary and phytosanitary documentation are in order for importing jurisdictions. Where antifreeze proteins are used in food, regulatory approvals and labelling in the importing market will determine market access and therefore trade flows. National biosafety rules and pharmaceutical regulatory frameworks can add further documentation requirements for medical applications.
Antifreeze Proteins Market Regional Analysis
North America Dominated the Antifreeze Proteins Market in 2024
North America dominated the antifreeze proteins market in 2024 due to higher demand for clean-label, organic, and natural ingredients in the food and beverage industry, for plant-based and sustainable food options, and other similar factors. Higher demand for convenient, sustainable, plan-based snack options also helps fuel the market's growth in the region. Countries such as the US and Canada play a major role in the growth of the regional market due to higher demand for frozen snacks and greater use of antifreeze proteins for cryopreservation and other medical applications.
Asia Pacific is Expected to Grow in the Forecast Period
Asia Pacific is expected to be the fastest-growing region over the forecast period due to high demand for natural and organic substitutes for chemicals and preservatives in the food and beverage industry. Higher demand for plant-based, clean-label, organic, and healthier food options that require antifreeze proteins is another major factor driving the market’s growth. High use of technologically advanced antifreeze proteins to enhance product quality and texture also helps fuel market growth. Countries such as India, China, Japan, and South Korea have made major contributions to the growth of the regional market due to high demand for healthier, cleaner, and greener options.
Europe is Observed to Have Notable Growth in the Foreseeable Period
Europe is expected to see notable growth over the forecast period due to high demand for antifreeze proteins across various applications. The development of the food and beverage industry, enhanced food and beverage safety, and the use of advanced technology to improve the quality and texture of various food options are other major factors driving market growth. Countries such as France, Germany, and the UK have made major contributions to the market's growth in the region, driven by higher demand for innovation in the food and beverage industry, further fueling the market's expansion.
Antifreeze Proteins Market Report Scope
| Report Attribute | Key Statistics |
| Base Year | 2024 |
| Forecast Period | 2025 to 2034 |
| Growth Rate from 2025 to 2034 | CAGR of 28.6% |
| Market Size in 2025 | USD 17.43 Billion |
| Market Size in 2026 | USD 22.41 Billion |
| Market Size by 2034 | USD 167.63 Billion |
| Dominated Region | North America |
| Fastest Growing Region | Asia Pacific |
| Regions Covered | North America, Europe, Asia-Pacific, Latin America and Middle East & Africa |
Have Questions? Let’s Talk—Schedule a Meeting with Our Insights Team: https://www.towardsfnb.com/schedule-meeting
Antifreeze Proteins Market Segmental Analysis
Type Analysis
The antifreeze glycoproteins segment led the antifreeze proteins market in 2024 due to its higher usage in the biotechnology, food science, and cryopreservation. Antifreeze proteins help to prevent ice growth crystallization in organisms, bind to ice crystals, and lower the freezing point of the surrounding fluid. Such factors make them highly demanding for crop preservation, enhancing the quality of frozen food options, and protecting the preservation of organs and tissues, which are helpful for market growth.
The type III antifreeze protein segment is expected to grow over the forecast period as it inhibits ice crystal growth, supports cryopreservation, and protects cells from cold, further fueling market growth. Their unique globular structure, which helps protect cells from freezing and hypothermic damage, is another major factor driving market growth in the foreseeable future. Such properties make them ideal for biotechnological concepts, further fueling the market’s growth.
Source Analysis
The fish-derived antifreeze protein segment dominated the antifreeze protein market in 2024 due to a range of benefits, including recrystallization of ice crystals, inhibition of growth, lowering the non-colligative freezing point of water, enhancing membrane stabilization, and being effective and non-toxic at low concentrations. Some fish antifreeze proteins, such as types 1 and 3, help stabilize them during cold storage, further fueling market growth.
The recombinant antifreeze proteins market is expected to grow in the foreseen period due to its requirement for various applications, such as enhancing the shelf life of various food options, such as fish, meat, dough, and cream, along with enhancing the cryopreservation of cells procedure, along with targeted properties, customization, and functionality.
End Use Analysis
The food processors and seafood industry segment led the antifreeze proteins market in 2024 due to its benefits, such as enhancing shelf life and improving the taste, texture, and quality of seafood and meat products. It also helps reduce water migration and drip loss, enhancing product quality and making it premium, which is further helpful for the segment's growth.
The pharmaceutical and biotech companies segment is expected to grow over the forecast period due to demand for high-quality protein options, increased demand for functional food and beverages, rising awareness of health and wellness, and scalability to produce high-quality proteins, which will help drive market growth. Increasing consumer preference for organic, clean-label, healthier, and plant-based protein options is another major factor driving the market’s growth in the foreseeable future.
Feel Free to Get in Touch with Us for Orders or Any Questions at: sales@towardsfnb.com
Additional Topics Worth Exploring:
- Tea Market: The global tea market size is projected to expand from USD 30.25 billion in 2025 to USD 54.68 billion by 2034, growing at a CAGR of 6.8% during the forecast period from 2025 to 2034
- Beverage Packaging Market: The global beverage packaging market size is projected to reach USD 271.80 billion by 2034, growing from USD 173.71 billion in 2025, at a CAGR of 5.1% during the forecast period from 2025 to 2034.
- Gluten Free Food Market: The global gluten free food market size increasing from USD 14.25 billion in 2025 and is expected to surpass USD 33.59 billion by 2034, with a projected CAGR of 10% during the forecast period from 2025 to 2034.
- Canned Wines Market: The global canned wines market size is expected to increase from USD 127.88 million in 2025 to USD 332.46 million by 2034, growing at a CAGR of 11.2% throughout the forecast period from 2025 to 2034.
- Plant-Based Protein Market: The global plant-based protein market size is projected to expand from USD 20.33 billion in 2025 and is expected to reach USD 43.07 billion by 2034, growing at a CAGR of 8.7% during the forecast period from 2025 to 2034.
- Bakery Product Market: The global bakery product market size is rising from USD 507.46 billion in 2025 to USD 821.62 billion by 2034. This projected expansion reflects a CAGR of 5.5% during the forecast period from 2025 to 2034.
- Coconut Products Market: The global coconut products market size is expected to climb from USD 14.18 billion in 2025 to approximately USD 33.71 billion by 2034, growing at a CAGR of 10.1% during the forecast from 2025 to 2034.
- Pet Food Market: The global pet food market size is expected to increase from USD 113.02 billion in 2025 to USD 167.97 billion by 2034, growing at a CAGR of 4.5% throughout the estimated timeframe from 2025 to 2034.
-
Organic Food Market: The global organic food market size is expected to grow from USD 253.96 billion in 2025 to USD 660.25 billion by 2034, with a compound annual growth rate (CAGR) of 11.20% during the forecast period from 2025 to 2034.
Top Companies in the Antifreeze Proteins Market
- Unilever – Unilever conducts significant research on antifreeze protein applications, particularly in ice cream formulations, to improve texture, reduce ice crystal growth, and enhance product stability during temperature fluctuations. The company integrates protein based solutions to maintain quality in frozen desserts.
- Kaneka Corporation – Kaneka develops functional proteins and biochemical ingredients, including antifreeze proteins for food preservation and biotechnology applications. Its innovations support improved freeze stability in food, cosmetic, and biomedical formulations.
- Nichirei Corporation – Nichirei works with antifreeze proteins for frozen food innovation, focusing on maintaining product quality, texture, and freshness during low temperature storage. The company leverages natural AFP sources for improved shelf life.
- A/F Protein Inc. – A/F Protein specializes in producing recombinant antifreeze proteins originally derived from cold water fish. Its products are used in food processing, cryopreservation, and agricultural applications requiring freeze protection.
- Sirona Biochem – Sirona Biochem develops carbohydrate based antifreeze protein analogues designed to protect cells, tissues, and formulations from freeze damage. Its technology has applications in cosmetics, dermatology, and biotherapeutics.
- ProtoKinetix, Inc. – ProtoKinetix produces AAGP molecules, which mimic the action of antifreeze proteins to protect biological materials during cold storage. These molecules are used in cell therapies, biobanking, and organ preservation research.
- AquaBounty Technologies, Inc. – AquaBounty utilizes antifreeze protein technology in aquaculture, particularly for genetic enhancement of cold tolerance in salmon. This helps improve production efficiency and expand farming into colder environments.
- Shanghai Yu Tao Industrial Co., Ltd. – The company supplies antifreeze protein ingredients for industrial and food applications. Its products support freeze resistance in processed foods, beverages, and biotechnological formulations.
- Beijing Huacheng Jinke Technology Co., Ltd. – This company develops AFP based biomaterials and functional ingredients used in frozen food processing, agricultural protection, and biotechnology.
- Kodera Herb Garden Co., Ltd. – Kodera produces natural botanical and biological extracts, including antifreeze related ingredients used in cosmetics, agricultural enhancement, and freeze protection formulations.
- Rishon Biochem Co., Ltd. – Rishon Biochem supplies biochemical ingredients including antifreeze proteins for food technology, cryopreservation, and specialty frozen products.
- MyBioSource, Inc. – MyBioSource offers research grade antifreeze proteins, recombinant AFPs, and related antibodies for laboratory use. These are used in academic and commercial research related to cryobiology and biotechnology.
- BASF SE – BASF develops biochemical and functional ingredient technologies that include antifreeze inspired solutions for personal care and industrial applications. Its ingredients help protect formulations from cold related degradation.
- Cargill, Incorporated – Cargill explores antifreeze proteins for improving frozen food quality, especially in dairy and dessert applications. Its research includes natural AFP sources and protein based stabilization systems.
-
AFP Biosciences – AFP Biosciences develops antifreeze proteins and cryoprotective ingredients for food, biopharmaceutical, and agricultural uses. The company focuses on scalable AFP production and application specific formulations.
Segments Covered in the Report
By Type
- Type I AFP
- Type II AFP
- Type III AFP
- Type IV AFP
- Antifreeze Glycoproteins (AFGPs)
By Source
- Fish-Derived AFPs
- Plant-Derived AFPs
- Insect-Derived AFPs
- Recombinant / Synthetic AFPs
By End-User
- Food Processors & Seafood Industry
- Pharmaceutical & Biotech Companies
- Cosmetic Manufacturers
- Academic & Research Institutions
- Agricultural Biotech Firms
By Region
North America
- U.S.
- Canada
Asia Pacific
- China
- Japan
- India
- South Korea
- Thailand
Europe
- Germany
- UK
- France
- Italy
- Spain
- Sweden
- Denmark
- Norway
Latin America
- Brazil
- Mexico
- Argentina
Middle East and Africa (MEA)
- South Africa
- UAE
- Saudi Arabia
- Kuwait
Thank you for exploring our insights. For more targeted information, customized chapter-wise sections and region-specific editions such as North America, Europe, or Asia Pacific—are also available upon request.
For Detailed Pricing and Tailored Market Report Options, Click Here: https://www.towardsfnb.com/checkout/5913
Feel Free to Get in Touch with Us for Orders or Any Questions at: sales@towardsfnb.com
Unlock expert insights, custom research, and premium support with the Towards FnB Annual Membership. For USD 495/month (billed annually), get full access to exclusive F&B market data and personalized guidance. It’s your strategic edge in the food and beverage industry: https://www.towardsfnb.com/get-an-annual-membership
About Us
Towards FnB is a global consulting firm specializing in the food and beverage industry, providing innovative solutions and expert guidance to elevate businesses. With an in-depth understanding of the dynamic F&B sector, we deliver customized market analysis and strategic insights. Our team of seasoned professionals is committed to empowering clients with the knowledge needed to make informed decisions, ensuring they stay ahead of market trends. Partner with us as we redefine success in the rapidly evolving food and beverage landscape, and together, we’ll navigate this transformative journey.
Web: https://www.towardsfnb.com/
Our Trusted Data Partners
Precedence Research | Statifacts | Towards Packaging | Towards Chemical and Materials| Nova One Advisor | Food Beverage Strategies | FnB Market Pulse | Nutraceuticals Func Foods | Onco Quant | Sustainability Quant | Specialty Chemicals Analytics
For Latest Update Follow Us:
Discover More Market Trends and Insights from Towards FnB:
➡️Beverage Flavors Market: https://www.towardsfnb.com/insights/beverage-flavors-market
➡️Salt Market: https://www.towardsfnb.com/insights/salt-market
➡️Probiotic Food Market: https://www.towardsfnb.com/insights/probiotic-food-market
➡️Protein Bar Market: https://www.towardsfnb.com/insights/protein-bar-market
➡️Gluten-Free Bakery Market: https://www.towardsfnb.com/insights/gluten-free-bakery-market
➡️Europe Nutraceuticals Market: https://www.towardsfnb.com/insights/europe-nutraceuticals-market
➡️Canned Food Market: https://www.towardsfnb.com/insights/canned-food-market
➡️Non-Alcoholic Beverages Market: https://www.towardsfnb.com/insights/non-alcoholic-beverages-market
➡️Dry Fruit Market: https://www.towardsfnb.com/insights/dry-fruit-market
➡️Frozen Meat Market: https://www.towardsfnb.com/insights/frozen-meat-market
➡️Fish Oil Market: https://www.towardsfnb.com/insights/fish-oil-market
➡️Soft Drink Concentrates Market: https://www.towardsfnb.com/insights/soft-drink-concentrates-market
Legal Disclaimer:
EIN Presswire provides this news content "as is" without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above.
